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Canadian Journal of Cardiology

A Single Mediterranean-Type Meal Leads to Postprandial Enrichment in Omega-3 Pufas and Does Not Impair Flow-Mediated Dilatation in Comparison to a High-Saturated Fat Meal in Healthy Men With High-Normal Fasting Triglyceridemia

      Fasting triglyceridemia in the pathological range exacerbates postprandial endothelial dysfunction - an early atherogenic step - induced by high-saturated fatty acid meal (HSFAM) ingestion. The influence of high, but normal fasting triglyceridemia (hnTG) on the endothelial response to HSFAM and the potential benefits exerted by a mixed Mediterranean-type meal (MMM) on postprandial endothelial function have never been investigated. Our objective was thus 1) to evaluate macro and microvascular and metabolic responses to a MMM in comparison to an isocaloric HSFAM in healthy males and 2) to explore the influence of hnTG on these measures.
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