The Look AHEAD (Action for Health in Diabetes) trial published recently in the New England Journal of Medicine reported that intensive lifestyle intervention focusing on weight loss did not reduce
morbidity and mortality in patients with obese type 2 diabetes over a 9.6-year follow-up
period.
1
However, after the first year, body mass, waist circumference, and glycated hemoglobin
levels again increased and physical fitness decreased, suggesting a lack of long-term
adherence to interventions.
1
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References
- Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes.N Engl J Med. 2013; 369: 145-154
- Weight loss with a low-carbohydrate, Mediterranean, or low-fat diet.N Engl J Med. 2008; 359: 229-241
- Primary prevention of cardiovascular disease with a Mediterranean diet.N Engl J Med. 2013; 368: 1279-1290
- The potential for high-intensity interval training to reduce cardiometabolic disease risk.Sports Med. 2012; 42: 489-509
Article info
Publication history
Published online: December 05, 2013
Identification
Copyright
© 2014 Canadian Cardiovascular Society. Published by Elsevier Inc. All rights reserved.
