Abstract
Background
Methods
Results
Conclusions
Résumé
Introduction
Méthodes
Résultats
Conclusions
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Canadian Journal of CardiologyReferences
- Global data on visual impairment in the year 2002.Bull World Health Organ. 2004; 82: 844-851
- Trends in cost of major eye disease to Medicare, 1991 to 2000.Am J Ophthalmol. 2006; 142: 976-982
- Human cholesterol metabolism and therapeutic molecules.Exp Physiol. 2008; 93: 27-42
- Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170 000 participants in 26 randomized trials.Lancet. 2010; 376: 1670-1681
- Statins for the primary prevention of cardiovascular disease.Cochrane Database Syst Rev. 2013; 1: CD004816
- On the etiology of subcapsular lenticular opacities produced in dogs receiving HMG-CoA reductase inhibitors.Exp Eye Res. 1990; 50: 65-78
- Unintended effects of statin in men and women in England and Wales: population based cohort study using the QResearch database.BMJ. 2010; 340: c2197
- Age-related cataract is associated with type 2 diabetes and statin use.Optom Vis Sci. 2012; 89: 1165-1171
- Association of statin use with cataracts: a propensity score-matched analysis.JAMA. 2013; 131: 1427-1434
- Statin use and cataract surgery: a nationwide retrospective cohort study in elderly ethnic Chinese patients.Drug Saf. 2013; 36: 1017-1024
- Absence of effect of simvastatin on the progression of lens opacities in a randomized placebo controlled study.Br J Ophthalmol. 1995; 79: 996-1002
- Cataract and the use of statins: a case-control study.Q J Med. 2003; 96: 337-343
- Risk of cataract in patients treated with statins.Arch Intern Med. 2001; 161: 2021-2026
- MF Rousseau. Statin therapy and cataract in type 2 diabetes.Diabetes Metab. 2011; 37: 139-143
- Persistence with statins and incident cataract: a population based historical cohort study.Ann Epidemiol. 2010; 20: 136-142
- Statin use and incident nuclear cataract.JAMA. 2006; 295: 2752-2758
- Statin use and the long term risk of incident cataract: the Blue Mountains eye study.Am J Ophthalmol. 2007; 143: 687-689
- Recent statin use and cataract surgery.Am J Ophthalmol. 2012; 153: 222-228
Population Data BC. Discharge Abstracts Database (Hospital Separations file). Availbable at: http://www.popdata.bc.ca/data/internal/health/dad. Accessed June 23, 2013.
British Columbia Ministry of Health. Medical Services Plan of B.C. Available at: http://www.health.gov.bc.ca/msp/index.html. Accessed June 23, 2013.
British Columbia Ministry of Health. PharmaNet. Available at: http://www.health.gov.bc.ca/pharmacare/pharmanet/netindex.html. Accessed June 23, 2013.
- Risk of death in elderly users of conventional vs. atypical antipsychotic medications.N Engl J Med. 2005; 353: 2335-2341
- Oral fluoroquinolones and the risk of retinal detachment.JAMA. 2012; 307: 1414-1419
- The nested case-control study in cardiology.Am Heart J. 2003; 146: 581-590
- Withdrawal of cerivastatin from the world market.Curr Control Trials Cardiovasc Med. 2001; 2: 205-207
- Lanosterol synthase mutations cause cholesterol deficiency-associated cataracts in the shumiya cataract rat.J Clin Invest. 2006; 116: 395-404
- Cholesterol and cataracts.Surv Ophthalmol. 1996; 40: 320-337
- Clinical Ophthalmology: A Systematic Approach.7th Ed. Elsevier, Philadelphia2011
- Statin adverse effects: a review of the literature and evidence for a mitochondrial mechanism.Am J Cardiovasc Drugs. 2008; 8: 373-418
- Canadian Ophthalmological Society evidence-based clinical practice guidelines for cataract surgery in the adult eye.Can J Ophthalmol. 2008; 43: S7-57
Article info
Publication history
Footnotes
See editorial by Gryn et al., pages 1508-1510 in this issue.
See page 1618 for disclosure information.
Identification
Copyright
ScienceDirect
Access this article on ScienceDirectLinked Article
- Statins and Cataracts: Reverse Causality?Canadian Journal of CardiologyVol. 31Issue 5
- PreviewThe report of Wise et al.,1 on increased risk of cataracts among patients who receive statins, is burdened by the risk of reverse causality inherent in such observational studies. Perhaps the best known example of this problem is the report from a US Health Cooperative, (see Supplemental Reference S1) that patients taking calcium channel antagonists had a greater risk of myocardial infarction, leading to an enormous tempest in a teapot. This fiasco was finally understood when it became apparent that the patients were receiving calcium channel antagonists for angina.
- Full-Text
- Preview