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Canadian Journal of Cardiology

The Metabolic Syndrome Is an Important Concept in Therapeutic Decision-Making

Published:November 05, 2014DOI:https://doi.org/10.1016/j.cjca.2014.10.037

      Abstract

      Traditional risk factors can underestimate the true risk of developing atherosclerotic cardiovascular disease. Abdominal obesity is associated with a cluster of risk factors that include dyslipidemia, dysglycemia, and hypertension, termed metabolic syndrome (MS). The presence of MS increases cardiovascular risk 50%-100% beyond that defined according to traditional risk factors, and increases the risk of developing type 2 diabetes. Recognition of patients with MS is important to: (1) identify patients at increased risk beyond that conveyed by traditional risk factors; and (2) understand that the metabolic abnormalities associated with MS are largely reversed by measures that reduce abdominal obesity.

      Résumé

      Les facteurs de risque traditionnels peuvent sous-estimer le risque réel de développement de maladies cardiovasculaires athérosclérotiques. L’obésité abdominale est associée à un ensemble de facteurs de risque comprenant la dyslipidémie, la dysglycémie et l’hypertension que l’on nomme le syndrome métabolique (SM). La présence du SM accroît le risque cardiovasculaire de 50 % à 100 % au-delà de celui qui est défini en fonction des facteurs de risque traditionnels, et accroît le risque de développement du diabète de type 2. La détection des patients souffrant du SM est importante pour : 1) déterminer les patients exposés à un risque élevé au-delà du risque transmis par les facteurs de risque traditionnels; 2) comprendre que les anomalies métaboliques associées au SM se résorbent en grande partie grâce aux mesures qui réduisent l’obésité abdominale.
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