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Canadian Journal of Cardiology

A Global Perspective on Cardiovascular Disease in Vulnerable Populations

      Abstract

      Cardiovascular disease (CVD) is a major contributor to the growing public health epidemic in chronic diseases. Much of the disease and disability burden from CVDs are in people younger than the age of 70 years in low- and middle-income countries, formerly “the developing world.” The risk of CVD is heavily influenced by environmental conditions and lifestyle variables. In this article we review the scope of the CVD problem in low- and middle-income countries, including economic factors, risk factors, at-risk groups, and explanatory frameworks that hypothesize the multifactorial drivers. Finally, we discuss current and potential interventions to reduce the burden of CVD in vulnerable populations including research needed to evaluate and implement promising solutions for those most at risk.

      Résumé

      La maladie cardiovasculaire (MCV) contribue de manière importante au problème de santé publique croissant que représente l’épidémie de maladies chroniques. La majeure partie du fardeau de la MCV et de l’incapacité qu’elle occasionne touche les personnes âgées de moins de 70 ans vivant dans les pays à revenu faible ou intermédiaire, anciennement appelés « les pays en voie de développement ». Le risque de MCV est fortement déterminé par les conditions environnementales et le mode de vie. Dans cet article, nous nous penchons sur l’ampleur du problème posé par la MCV dans les pays à revenu faible ou intermédiaire, en examinant notamment les facteurs économiques, les facteurs de risque et les groupes à risque ainsi que les cadres explicatifs des hypothèses sur les multiples variables en cause. Enfin, nous analysons les interventions déjà en cours et les mesures susceptibles de réduire le fardeau de la MCV dans les populations vulnérables, y compris la réalisation des études requises pour pouvoir évaluer et mettre en place des solutions prometteuses ciblant les personnes les plus à risque.
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