Canadian Journal of Cardiology
Case Report| Volume 32, ISSUE 12, P1574.e9-1574.e10, December 2016

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Restored Physiological Vasomotion Imitating Intrascaffold Restenosis 3 Years After Bioresorbable Scaffold Implantation

Published:March 02, 2016DOI:


      Bioresorbable vascular scaffolds (BVSs) have recently been introduced into clinical practice; they have many potential advantages, 1 of which includes restoring physiological vasomotion. It has been shown that the degree of vasomotion is correlated with bioresorption. We present a case of intrascaffold spasm masquerading as restenosis 3 years after implantation, despite the ongoing process of bioresorption: intra-BVS vasospasm should therefore be considered and confirmed by intracoronary nitrate administration.


      Les échafaudages vasculaires biorésorbables (EVB) ont récemment fait leur entrée dans la pratique clinique. Ces dispositifs pourraient offrir de nombreux avantages dont l’un est le rétablissement de la vasomotricité physiologique. Une corrélation a été démontrée entre le degré de vasomotricité et la biorésorption. Nous présentons ici un cas de spasme intra-échafaudage déguisé en resténose trois ans après l’implantation, malgré la biorésorption constante. Il convient donc d’envisager la possibilité d’un vasospasme intra-EVB et de confirmer sa présence par l’administration intracoronarienne de nitrate.
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        • Onuma Y.
        • Serruys P.W.
        Bioresorbable scaffold: the advent of a new era in percutaneous coronary and peripheral revascularization?.
        Circulation. 2011; 123: 779-797
        • Brugaletta S.
        • Heo J.H.
        • Garcia-Garcia H.M.
        • et al.
        Endothelial-dependent vasomotion in a coronary segment treated by ABSORB everolimus-eluting bioresorbable vascular scaffold system is related to plaque composition at the time of bioresorption of the polymer: indirect finding of vascular reparative therapy.
        Eur Heart J. 2012; 33: 1325-1333
        • Sarno G.
        • Bruining M.
        • Onuma Y.
        • et al.
        Morphological and functional evaluation of the bioresorption of the bioresorbable everolimus-eluting vascular scaffold using IVUS, echogenicity and vasomotion testing at two year follow-up: a patient level insight into the ABSORB A clinical trial.
        Int J Cardiovasc Imaging. 2012; 28: 51-58
        • Serruys P.W.
        • Ormiston J.
        • van Geuns R.J.
        • et al.
        A polylactide bioresorbable scaffold eluting everolimus for treatment of coronary stenosis: 5-year follow-up.
        J Am Coll Cardiol. 2016; 67: 766-776