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Canadian Journal of Cardiology

Transcatheter Aortic Valve Replacement for Severe Aortic Stenosis in Women: Clinical Characteristics and Outcomes

Published:November 10, 2017DOI:https://doi.org/10.1016/j.cjca.2017.10.026

      Abstract

      Aortic stenosis (AS), 1 of the most common valve diseases in developed countries, carries a poor prognosis if left untreated. Transcatheter aortic valve replacement (TAVR) has become the standard of care for high-risk and inoperable patients with severe aortic stenosis (AS). Women represent a significant proportion of patients with severe AS and demonstrate specific clinical, anatomic, and pathophysiological features that are evident both before and after valve replacement. In this review, we discuss these features as well as the outcomes of women undergoing TAVR for AS.

      Résumé

      La sténose aortique (SA), l’une des valvulopathies les plus fréquentes dans les pays développés, engendre un pronostic défavorable s’il n’est pas traité. Le remplacement valvulaire aortique par cathéter (RVAC) est désormais la norme de soins chez les patients ayant une SA grave qui sont exposés à un risque élevé et qui sont inopérables. Les femmes représentent une proportion importante des patients ayant une SA grave et démontrent des caractéristiques cliniques, anatomiques et physiopathologiques particulières qui sont évidentes avant et après le remplacement valvulaire. Dans cette revue, nous nous penchons sur ces caractéristiques ainsi que sur l’évolution de l’état de santé des femmes qui subissent le RVAC en raison d’une SA.
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