Canadian Journal of Cardiology
Case Report| Volume 34, ISSUE 3, P342.e1-342.e3, March 2018

Zero-Contrast Percutaneous Coronary Intervention Guided by Dextran-Based Optical Coherence Tomography

Published:November 22, 2017DOI:


      Individuals with advanced chronic kidney disease (CKD) and coronary artery disease are often denied percutaneous coronary intervention (PCI) because of an aversion to the risk of contrast-induced nephropathy. We present the case of a 76-year-old man with stage 4 CKD requiring coronary revascularization. Zero-contrast PCI was successfully performed using dextran-based optical coherence tomography (OCT) guidance. Our report suggests the feasibility of dextran-based, OCT-guided, zero-contrast PCI in patients with advanced CKD. Further studies should evaluate the safety and efficacy of this novel approach.


      Les individus atteints de néphropathie chronique (NPC) de stade avancé et de coronaropathie se voient souvent refuser l’intervention coronarienne percutanée (ICP) en raison d’une aversion pour le risque de néphropathie induite par les produits de contraste. Nous présentons le cas d’un homme de 76 ans atteints d’une NPC de stade 4 pour laquelle une revascularisation coronarienne est nécessaire. L’ICP sans injection de produit de contraste a été réussie grâce au guidage par tomographie par cohérence optique (TCO) au dextrane. Notre rapport illustre la faisabilité de l’ICP sans injection de produit de contraste guidée par TCO au dextrane chez les patients atteints d’une NPC de stade avancé. Des études portant sur l’évaluation de l’innocuité et de l’efficacité de cette nouvelle approche devraient être réalisées.
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