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Canadian Journal of Cardiology
Editorial| Volume 36, ISSUE 7, P1003-1005, July 2020

Persistent Mitral Regurgitation After TAVR—Where to From Here?

  • Maneesh Sud
    Affiliations
    Schulich Heart Center, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
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  • Harindra C. Wijeysundera
    Correspondence
    Corresponding author: Dr Harindra C. Wijeysundera, Interventional Cardiology, Schulich Heart Centre, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Suite A202, Toronto, Ontario M4N 3M5, Canada.
    Affiliations
    Schulich Heart Center, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada

    Sunnybrook Research Institute, Toronto, Ontario, Canada

    Institute for Clinical Evaluative Sciences, Institute for Health Policy, Management, and Evaluation, Toronto, Ontario, Canada
    Search for articles by this author
Published:December 28, 2019DOI:https://doi.org/10.1016/j.cjca.2019.12.016
      In patients undergoing surgical aortic valve replacement (SAVR) for severe aortic stenosis (AS), guidelines generally recommend mitral valve repair or replacement for patients with severe mitral regurgitation (MR), whereas the decision to intervene in moderate MR is less certain.
      • Nishimura R.A.
      • Otto C.M.
      • Bonow R.O.
      • et al.
      2014 AHA/ACC guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.
      Despite the fact that these indications to intervene on the mitral valve were derived mainly from observational data and expert opinion, it is felt that the 2-fold increase in surgical risk of a double valve intervention over a single AVR is justified when severe MR is present but debatable when moderate MR is present.
      • Iung B.
      • Baron G.
      • Butchart E.G.
      • et al.
      A prospective survey of patients with valvular heart disease in Europe: the Euro Heart Survey on Valvular Heart Disease.
      With the emergence of transcatheter aortic valve replacement (TAVR) as a viable and often preferable treatment strategy for patients with AS,
      • Asgar A.W.
      • Ouzounian M.
      • Adams C.
      • et al.
      2019 Canadian Cardiovascular Society position statement for transcatheter aortic valve implantation.
      there is a growing need to reevaluate the role, timing, and mode of mitral valve intervention for concomitant MR.
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