Intramyocardial hemorrhage (IMH), coupled with microvascular obstruction (MVO), is
an independent predictor of adverse remodelling following ST-segment elevation myocardial
infarction (STEMI)
1
. In the acute phase (<3 days) of MI, MVO, and IMH concurrently occur in 40% to 60%
of patients presenting with STEMI and typically resolve by 1 to 3 months post-MI.
1
However, recent studies have offered evidence that IMH, although not MVO, can persist
even up to the chronic phase (>2 months) and is associated with greater inflammation,
adverse remodelling and poorer outcomes.
2
,3
In this study, we exploited the comprehensive nature of cardiovascular magnetic resonance
(CMR) imaging to highlight a unique STEMI case exhibiting the chronic presentation
of both IMH and MVO, along with heightened inflammation.To read this article in full you will need to make a payment
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References
- Myocardial hemorrhage after acute reperfused ST-segment-elevation myocardial infarction: relation to microvascular obstruction and prognostic significance.Circ Cardiovasc Img. 2016; 9e004148
- Residual myocardial iron following intramyocardial hemorrhage during the convalescent phase of reperfused ST-segment elevation myocardial infarction and adverse left ventricular remodeling.Circ Cardiovasc Img. 2016; 9
- Hemorrhage promotes inflammation and myocardial damage following acute myocardial infarction: insights from a novel preclinical model and cardiovascular magnetic resonance.J Cardiovasc Magn Reson. 2017; 19: 50
- Chronic manifestation of postreperfusion intramyocardial hemorrhage as regional iron deposition: a cardiovascular magnetic resonance study with ex vivo validation.Circ Cardiovasc Img. 2013; 6: 218-228
Article info
Publication history
Published online: April 06, 2020
Accepted:
March 27,
2020
Received:
March 6,
2020
Footnotes
See page 1326.e17 for disclosure information.
Identification
Copyright
© 2020 Canadian Cardiovascular Society. Published by Elsevier Inc. All rights reserved.