Canadian Journal of Cardiology
Case Report| Volume 37, ISSUE 8, P1278-1280, August 2021

Successful Therapy With Ticagrelor in Three-Vessel Stent Thrombosis Related to Clopidogrel Resistance

Published:March 25, 2021DOI:


      A 65-year-old man developed 3-vessel stent thrombosis after percutaneous coronary intervention with aspirin and clopidogrel. Platelet tests revealed clopidogrel resistance, which resolved after changing clopidogrel to ticagrelor. Although routine platelet tests after stenting are not recommended, these tests may be considered to identify the cause of stent thrombosis and modify antiplatelet therapy.


      Un homme de 65 ans a développé une thrombose de l'endoprothèse au niveau de trois vaisseaux après une intervention coronarienne percutanée sous aspirine et clopidogrel. Les tests de la fonction plaquettaire ont révélé une résistance au clopidogrel, qui s'est résolue après remplacement du clopidogrel par le ticagrelor. Bien que les tests de la fonction plaquettaire de routine après la pose d'une endoprothèse ne soient pas recommandés, ces tests peuvent être envisagés pour identifier la cause de la thrombose liée à l'endoprothèse et modifier le traitement antiplaquettaire.
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