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Case Report| Volume 37, ISSUE 10, P1661-1664, October 2021

Rubidium-82 Positron Emission Tomography With Intravenous Ergonovine to Diagnose Vasospastic Angina

  • Author Footnotes
    ‡ The authors contributed equally to this work and share corresponding authorship.
    E. Marc Jolicœur
    Correspondence
    Corresponding authors: Dr E. Marc Jolicœur, CHUM, 1051 Sanguinet, Montréal, Québec H2 × 3E4, Canada.
    Footnotes
    ‡ The authors contributed equally to this work and share corresponding authorship.
    Affiliations
    Centre Hospitalier de l'Université de Montréal, Montréal, Québec, Canada
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  • Author Footnotes
    ‡ The authors contributed equally to this work and share corresponding authorship.
    Matthieu Pelletier-Galarneau
    Correspondence
    Dr Matthieu Pelletier-Galarneau, Montreal Heart Institute, 5000 Bélanger Est, Montréal, Québec H1T 1C8, Canada. Tel.: +1-514-376-3330 x4418; fax: +1-514-376-0936.
    Footnotes
    ‡ The authors contributed equally to this work and share corresponding authorship.
    Affiliations
    Montréal Heart Institute, Montréal, Québec, Canada
    Search for articles by this author
  • Author Footnotes
    ‡ The authors contributed equally to this work and share corresponding authorship.
Published:March 31, 2021DOI:https://doi.org/10.1016/j.cjca.2021.03.020
Rubidium-82 Positron Emission Tomography With Intravenous Ergonovine to Diagnose Vasospastic Angina
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      Abstract

      The gold standard to diagnose vasospastic angina is intracoronary reactivity testing, which is performed selectively at dedicated centres. Noninvasive imaging with single-photon emission computerized tomography (SPECT) or echocardiography does not enable accurate localization of spasm or quantification of change in myocardial perfusion in response to an abnormal vasoreactivity. Rubidium-82 positron emission tomography myocardial perfusion imaging (82Rb PET-MPI) with intravenous ergonovine was used to diagnose refractory vasospastic angina in a patient with a complex ischemic syndrome, recent coronary stenting, and persistent atypical angina despite maximal tolerable doses of guideline-directed medical therapy.

      Résumé

      Le test de référence pour diagnostiquer l'angine vasospastique est le test de réactivité intracoronaire, qui est réalisé de manière sélective dans des centres spécialisés. L'imagerie non invasive telle que la tomographie par émission monophotonique assistée par ordinateur (SPECT) ou l'échocardiographie ne permet pas de localiser précisément le spasme ni de quantifier la modification de la perfusion myocardique en réponse à une vasoréactivité anormale. L'imagerie de perfusion myocardique par tomographie par émission de positons avec le rubidium-82 (TEP-Rb) avec ergonovine en intraveineuse a été utilisée pour diagnostiquer une angine vasospastique réfractaire chez un patient présentant un syndrome ischémique complexe, une pose récente d'une endoprothèse coronaire et une angine atypique persistante malgré les doses maximales tolérables du traitement médical recommandé.
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      Article info

      Publication history

      Published online: March 31, 2021
      Accepted: March 26, 2021
      Received: January 5, 2021

      Footnotes

      See page 1664 for disclosure information.

      Identification

      DOI: https://doi.org/10.1016/j.cjca.2021.03.020

      Copyright

      © 2021 Canadian Cardiovascular Society. Published by Elsevier Inc. All rights reserved.

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