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Canadian Journal of Cardiology
Editorial| Volume 37, ISSUE 8, P1159-1162, August 2021

A Simple, Reliable, and Validated Preoperative Cardiac Risk Index

  • W. Scott Beattie
    Correspondence
    Corresponding author: Dr W. Scott Beattie, Department of Anesthesia and Pain Management, University of Toronto, Toronto, Ontario, Canada. Tel.: +1-416-340-4800 ext 3227; fax: +1-416-340-3698.
    Affiliations
    Department of Anesthesia and Pain Management, University of Toronto, Toronto, Ontario, Canada and the Toronto General Research Institute, Toronto, Ontario, Canada
    Search for articles by this author
      Cardiac complications lead to postoperative disability and death.
      • Howell SJ
      • Brown OI
      • Beattie WS.
      Aetiology of perioperative myocardial injury: a scientific conundrum with profound clinical implications.
      ,
      • Beattie WS.
      The emergence of a postoperative myocardial injury epidemic: true or false.
      Preoperative cardiac risk stratification provides an opportunity to implement risk reduction, optimise the use of scarce resources, assess the quality of care, and facilitate clinical research.
      • Biccard B.
      Proposed research plan for the derivation of a new cardiac risk index.
      The Revised Cardiac Risk Index
      • Lee TH
      • Marcantonio ER
      • Mangione CM
      • et al.
      Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery.
      (RCRI) has gained wide acceptance for noncardiac surgery risk stratification. The original publication found that the 6 factors, presented in Table 1, discriminated well across mixed noncardiac surgical procedures (area under the receiver operating characteristic curve [AUC] 0.79). A 2010 systematic review identified 24 studies that included 800,000 patients and found that the RCRI performed as well as in the original analysis. (pooled AUC 0.75, 95% confidence interval [CI] 0.79-0.72).
      • Ford MK
      • Beattie WS
      • Wijeysundera DN.
      Systematic review: prediction of perioperative cardiac complications and mortality by the revised cardiac risk index.
      Taken together, these results show the RCRI to be accurate, easy to use, and generalisable, thus making it an almost ideal tool for clinical use.
      Table 1The revised cardiac risk index
      Risk factor Definition
      High-risk surgery a) Intraperitoneal

      b) Intrathoracic

      c) Supra-inguinal vascular
      History of ischemic heart disease a) History of myocardial infarction

      b) History of positive exercise test

      c) Current chest pain due to myocardial ischemia

      d) Use of nitrate therapy

      e) Electrocardiogram with pathologic Q waves
      History of congestive heart failure a) Pulmonary edema,

      b) Bilateral rales or S3 gallop

      c) Paroxysmal nocturnal dyspnea

      d) X-ray showing pulmonary vascular redistribution
      History of cerebrovascular disease a) Prior transient ischemic attack

      b) Stroke
      Preoperative treatment with insulin
      Chronic renal failure a) Preoperative creatinine > 177 µmol/L
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