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Canadian Journal of Cardiology
Brief Rapid Report| Volume 37, ISSUE 10, P1507-1512, October 2021

Temporal Trends in Hospitalization for Lower Extremity Peripheral Artery Disease in Ontario: The Importance of Diabetes

  • Jean Jacob-Brassard
    Correspondence
    Corresponding author: Dr Jean Jacob-Brassard, St Michael's Hospital, 30 Bond St, Office Donnelly 6-030, Toronto, Ontario M5B 1W8, Canada. Tel.: +1-416-360-4000.
    Affiliations
    Department of Surgery, University of Toronto, Toronto, Ontario, Canada

    Li Ka Shing Knowledge Institute of St Michael's Hospital, Toronto, Ontario, Canada
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  • Mohammed Al-Omran
    Affiliations
    Department of Surgery, University of Toronto, Toronto, Ontario, Canada

    Li Ka Shing Knowledge Institute of St Michael's Hospital, Toronto, Ontario, Canada

    Department of Surgery, King Saud University, Riyadh, Kingdom of Saudi Arabia
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  • Mohamad A. Hussain
    Affiliations
    Li Ka Shing Knowledge Institute of St Michael's Hospital, Toronto, Ontario, Canada

    Division of Vascular and Endovascular Surgery and the Centre for Surgery and Public Health, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA
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  • Muhammad Mamdani
    Affiliations
    Li Ka Shing Knowledge Institute of St Michael's Hospital, Toronto, Ontario, Canada

    ICES, Toronto, Ontario, Canada

    Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada

    Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada

    Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada

    Data Science and Advanced Analytics, Unity Health Toronto, Toronto, Ontario, Canada
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  • Thérèse A. Stukel
    Affiliations
    ICES, Toronto, Ontario, Canada

    Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada
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  • Douglas S. Lee
    Affiliations
    ICES, Toronto, Ontario, Canada

    Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada

    Peter Munk Cardiac Centre and the Joint Department of Medical Imaging at the University Health Network, Toronto, Ontario, Canada
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  • Charles de Mestral
    Affiliations
    Department of Surgery, University of Toronto, Toronto, Ontario, Canada

    Li Ka Shing Knowledge Institute of St Michael's Hospital, Toronto, Ontario, Canada

    ICES, Toronto, Ontario, Canada

    Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada
    Search for articles by this author

      Abstract

      We sought to assess temporal trends in peripheral artery disease (PAD)-related hospitalization rates in Ontario. Trends in quarterly rates of PAD hospitalization per 100,000 Ontarians between 2006 and 2019 were assessed using autocorrelated linear regression. Stratified analyses according to age, sex, and most responsible diagnosis code type (with vs without diabetes-specific PAD codes) were performed. From 2006 to 2019, overall PAD hospitalizations did not decrease significantly when diabetes-specific codes were included. A significant decrease was observed among women and those older than 65 years old. Future studies of PAD epidemiology and outcomes using administrative data should include diabetic angiopathy.

      Résumé

      Nous avons cherché à évaluer les tendances temporelles des taux d'hospitalisation liés aux maladies artérielles périphériques (MAP) en Ontario. Les tendances des taux trimestriels d'hospitalisation liés aux MAP par tranches de 100 000 Ontariens entre 2006 et 2019 ont été évaluées par régression linéaire autocorrélée. Des analyses stratifiées ont été effectuées en fonction de l’âge, du sexe et du type de code diagnostique le plus significatif (avec vs sans codes de MAP faisant référence au diabète). De 2006 à 2019, les hospitalisations liées aux MAP n'ont dans l'ensemble pas diminué de façon notable après l'ajout de codes faisant référence au diabète. Une diminution significative a été observée chez les femmes et les personnes de plus de 65 ans. Les études ultérieures sur l’épidémiologie et l'issue des MAP qui seront réalisées à partir de données administratives devraient inclure l'angiopathie diabétique.
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      Linked Article

      • The Peripheral Arterial Disease Pandemic: No Let-up in Sight
        Canadian Journal of CardiologyVol. 37Issue 10
        • Preview
          In a recent systematic review it was estimated that the global prevalence of peripheral artery disease (PAD) was 5.6%, with higher prevalence estimates in high-income countries than in low-income countries.1 Worldwide, a total of 237 million people aged 25 years and older were living with PAD in 2015.1 Patients with PAD are at elevated risk of major adverse limb events and major adverse cardiovascular events.2 Extensive evidence suggests that patients with PAD are undertreated with respect to vasculoprotective medications and lifestyle modification.
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