In a recent systematic review it was estimated that the global prevalence of peripheral
artery disease (PAD) was 5.6%, with higher prevalence estimates in high-income countries
than in low-income countries.
1
Worldwide, a total of 237 million people aged 25 years and older were living with
PAD in 2015.
1
Patients with PAD are at elevated risk of major adverse limb events and major adverse
cardiovascular events.
2
Extensive evidence suggests that patients with PAD are undertreated with respect
to vasculoprotective medications and lifestyle modification.
3
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References
- Global, regional, and national prevalence and risk factors for peripheral artery disease in 2015: an updated systematic review and analysis.Lancet Glob Health. 2019; 7 (e1020-30)
- Morbidity and mortality associated with atherosclerotic peripheral artery disease: a systematic review.Atherosclerosis. 2020; 293: 94-100
- Utilization of vasculoprotective therapy for peripheral artery disease: a systematic review and meta-analysis.Am J Med. 2018; 131 (e1333): 1332-1339
- Temporal trends in hospitalization for lower extremity peripheral artery disease in Ontario: the importance of diabetes.Can J Cardiol. 2021; 37: 1507-1512
- Recent trends in hospitalizations for cardiovascular disease, stroke, and vascular cognitive impairment in Canada.Can J Cardiol. 2020; 36: 1081-1090
- Complex evolution of epidemiology of vascular diseases, including increased disease burden: from 2000 to 2015.Can J Cardiol. 2020; 36: 740-746
- The prevalence of major lower limb amputation in the diabetic and non-diabetic population of England 2003-2013.Diab Vasc Dis Res. 2016; 13: 348-353
- Effectiveness of blood lipid management in patients with peripheral artery disease.J Am Coll Cardiol. 2021; 77: 3016-3027
- Frequency of care and mortality following an incident diagnosis of peripheral artery disease in the inpatient or outpatient setting: the ARIC (Atherosclerosis Risk in Communities) study.J Am Heart Assoc. 2018; 7e007332
Article info
Publication history
Published online: July 20, 2021
Accepted:
July 14,
2021
Received:
July 8,
2021
Footnotes
See article by Jacob-Brassard et al., pages 1507–1512 of this issue.
See page 1497 for disclosure information.
Identification
Copyright
© 2021 Canadian Cardiovascular Society. Published by Elsevier Inc. All rights reserved.
ScienceDirect
Access this article on ScienceDirectLinked Article
- Temporal Trends in Hospitalization for Lower Extremity Peripheral Artery Disease in Ontario: The Importance of DiabetesCanadian Journal of CardiologyVol. 37Issue 10
- PreviewWe sought to assess temporal trends in peripheral artery disease (PAD)-related hospitalization rates in Ontario. Trends in quarterly rates of PAD hospitalization per 100,000 Ontarians between 2006 and 2019 were assessed using autocorrelated linear regression. Stratified analyses according to age, sex, and most responsible diagnosis code type (with vs without diabetes-specific PAD codes) were performed. From 2006 to 2019, overall PAD hospitalizations did not decrease significantly when diabetes-specific codes were included.
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