Coronary artery calcification (CAC) adds technical challenge and complexity to percutaneous
coronary interventions (PCIs) and is associated with poorer outcomes and major adverse
cardiovascular events.
1
CAC can lead to stent malapposition, asymmetric expansion, and stent underexpansion,
which has been associated with higher rates of device-oriented composite endpoints
such as cardiac death, myocardial infarction related to the target vessel, or target-lesion
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References
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Tovar Forero MN, Sardella G, et al. Coronary lithotripsy for the treatment of underexpanded stents: the international multicentre CRUNCH registry. [e-pub ahead of print] EuroIntervention 2022. https://doi.org/10.4222/EIJ-D-21-00545.
Article Info
Publication History
Published online: June 14, 2022
Accepted:
June 10,
2022
Received:
June 4,
2022
Publication stage
In Press Journal Pre-ProofFootnotes
See article by Pham et al., pages xxx-xxx, of this issue.
See page 2 for disclosure information.
Identification
Copyright
© 2022 Canadian Cardiovascular Society. Published by Elsevier Inc. All rights reserved.
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- In-Stent Use of Intravascular Coronary Lithotripsy for Restenosis and Stent Underexpansion: A Multicentre ExperienceCanadian Journal of Cardiology
- PreviewPercutaneous coronary intervention (PCI) of severe calcified lesions is at high risk of complications (dissection, perforation, stent underexpansion, etc) and suboptimal results have been associated with major cardiac adverse events. Intravascular lithotripsy uses acoustic energy to disrupt the calcified plaque by creating microfractures. The Shockwave C2 (Shockwave Medical Inc, Santa Clara, CA) intravascular lithotripsy system (S-IVL) was approved by the Food and Drug Administration after studies confirming its safety and efficacy.
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