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Canadian Journal of Cardiology

Refining the Stratification and Prognosis of Cardiogenic Shock Patients to Improve Their Outcome

Published:September 05, 2022DOI:https://doi.org/10.1016/j.cjca.2022.09.001
      Cardiogenic shock (CS) remains associated with substantial morbidity and short-term mortality that often exceeds 40% despite contemporary therapy, and no recent randomized clinical trial has demonstrated an incremental improvement in outcomes.
      • van Diepen S.
      • Katz J.N.
      • Albert N.M.
      • et al.
      Contemporary management of cardiogenic shock: a scientific statement from the American Heart Association.
      There is a wide spectrum of risk within CS populations, with severalfold variation in the likelihood of short-term survival between groups. Risk-tailored treatment has been proposed in other acute cardiovascular conditions, such as acute myocardial infarction (AMI). In high-risk patients with AMI, a more aggressive treatment strategy might be associated with better outcomes; if the same could be shown in patients with severe CS, this could lead to individualized treatment and improved survivorship.
      • Jentzer J.C.
      • Rayfield C.
      • Soussi S.
      • et al.
      Advances in the staging and phenotyping of cardiogenic shock part 1: clinical context [e-pub ahead of print].
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