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Canadian Journal of Cardiology

Anakinra During Pregnancy in a Difficult to Treat Case of Recurrent Pericarditis

Published:October 25, 2022DOI:https://doi.org/10.1016/j.cjca.2022.10.020
      Anakinra, an anti–interleukin-1 agent, is a therapeutic option for recurrent pericarditis that is difficult to treat with conventional treatment (nonsteroidal anti-inflammatory drugs, colchicine, corticosteroids). It is also used in treatment of autoimmune and autoinflammatory diseases.
      • Serati L.
      • Carnovale C.
      • Maestroni S.
      • et al.
      Management of acute and recurrent pericarditis in pregnancy.
      ,
      • Adler Y.
      • Charron P.
      • Imazio M.
      • et al.
      2015 ESC guidelines for the diagnosis and management of pericardial diseases.
      Due to the increasing use of biologic drugs during childbearing age, there is a growing interest in their safety during reproduction and pregnancy.
      • Serati L.
      • Carnovale C.
      • Maestroni S.
      • et al.
      Management of acute and recurrent pericarditis in pregnancy.
      However, there are only a few cases reported about the use of anakinra during pregnancy, most in rheumatic diseases. We describe the first case report of a woman taking anakinra during both pregnancy and breastfeeding for idiopathic recurrent pericarditis.
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