Abstract
Background
This study aimed to clarify the variations in the quality of care provided to patients
with acute coronary syndrome (ACS) and to investigate the association between quality
of care and mortality at both hospital and patient levels with the use of a nationwide
database.
Methods
Patients with ACS who underwent percutaneous coronary intervention (PCI) from April
2014 to March 2018 were included from the National Database of Health Insurance Claims
and Specific Health Checkups of Japan. Twelve quality indicators (QIs) available from
administrative data and the association of the QIs with all-cause mortality were investigated.
Results
From the analysis of 216,436 patients from 1215 hospitals, adherence to PCI on admission
day, aspirin use on arrival, P2Y12 inhibitor use, and left ventricular function assessment
were high (median proportion > 90%), and adherence to outpatient cardiac rehabilitation
was low (median proportion < 10%). At the hospital level, acute-phase composite QI
score was associated with reduced risk-adjusted 30-day mortality (β = −0.92 [95% confidence
interval −1.19 to −0.65]; P < 0.001). At the patient level, all acute-phase and subacute-phase QIs were inversely
associated with 30-day and 2-year mortalities, respectively (all P < 0.001).
Conclusions
Substantial variations in ACS care were observed in the current nationwide database.
High adherence to the QI sets was associated with significant survival gains at both
hospital and patient levels. Multilevel approach in QI assessment may be effective
for improvement of survival in this population.
Résumé
Contexte
L’étude présentée ici visait à mieux comprendre les variations dans la qualité des
soins prodigués aux patients atteints d’un syndrome coronarien aigu (SCA) et à examiner,
à l’aide d’une base de données nationale, l’association entre la qualité des soins
et la mortalité à l’échelle des hôpitaux et des patients.
Méthodologie
Ont été inclus dans l’étude les patients atteints d’un SCA qui ont subi une intervention
coronarienne percutanée (ICP) entre avril 2014 et mars 2018, selon la base de données
japonaise sur les demandes de remboursement d’assurance maladie et des bilans de santé
particuliers. Douze indicateurs de la qualité (IQ) tirés des données administratives
de même que l’association entre ces IQ et la mortalité toutes causes confondues ont
fait l’objet d’un examen.
Résultats
L’analyse des données de 216 436 patients traités dans 1215 hôpitaux a révélé que
la réalisation d’une ICP le jour de l’admission, l’administration d’aspirine à l’arrivée,
l’emploi d’un inhibiteur du récepteur P2Y12 et l’évaluation de la fonction ventriculaire
gauche étaient des mesures fréquentes (proportion médiane > 90 %), tandis que le recours
à la réadaptation cardiaque en consultation externe était rare (proportion médiane
< 10 %). En ce qui concerne les hôpitaux, l’indice composite pour les IQ relatifs
aux soins de phase aiguë a été associé à une réduction de la mortalité à 30 jours
ajustée en fonction du risque (β = −0,92 [intervalle de confiance à 95 % : −1,19 à −0,65];
p < 0,001). Chez les patients, tous les IQ relatifs aux soins de phase aiguë ou subaiguë
étaient inversement associés à la mortalité à 30 jours et à 2 ans (p < 0,001 dans les deux cas).
Conclusions
L’analyse des renseignements tirés d’une base de données nationale à jour révèle des
variations importantes dans les soins prodigués aux patients atteints d’un SCA. Une
forte observance des mesures correspondant aux ensembles d’IQ était associée à des
gains importants sur le plan de la survie, tant à l’échelle des hôpitaux que des patients.
Une approche multiniveau de l’évaluation des IQ pourrait donc permettre d’améliorer
la survie dans cette population de patients.
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References
- Global, regional, and national age-sex specific mortality for 264 causes of death, 1980-2016: a systematic analysis for the Global Burden of Disease Study 2016.Lancet. 2017; 390: 1151-1210
- Global and regional patterns in cardiovascular mortality from 1990 to 2013.Circulation. 2015; 132: 1667-1678
- 2017 AHA/ACC clinical performance and quality measures for adults with ST-elevation and non-ST-elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on performance measures.J Am Coll Cardiol. 2017; 70: 2048-2090
- 2020 update of the quality indicators for acute myocardial infarction: a position paper of the Association for Acute Cardiovascular Care: the Study Group for Quality Indicators from the ACVC and the NSTE-ACS Guideline Group.Eur Heart J Acute Cardiovasc Care. 2021; 10: 224-233
- Assessment of quality indicators for acute myocardial infarction in the FAST-MI (French registry of acute ST-elevation or non–ST-elevation myocardial infarction) registries.Circ Cardiovasc Qual Outcomes. 2017; 10e003336
- Assessment of quality indicators for acute myocardial infarction management in 28 countries and use of composite quality indicators for benchmarking.Eur Heart J Acute Cardiovasc Care. 2020; 9: 911-922
- Guideline-indicated treatments and diagnostics, GRACE risk score, and survival for non–ST elevation myocardial infarction.Eur Heart J. 2018; 39: 3798-3806
- Achievement of guideline-concordant care and in-hospital outcomes in patients with coronary artery disease in teaching and nonteaching hospitals: results from the Get With The Guidelines—Coronary Artery Disease program.Circ Cardiovasc Qual Outcomes. 2013; 6: 58-65
- Sex differences in quality indicator attainment for myocardial infarction: a nationwide cohort study.Heart. 2019; 105: 516-523
- Real world data in Japan: chapter I: NDB.Ann Clin Epidemiol. 2019; 1: 28-30
Kubo S, Noda T, Myojin T, Yuichi N. National database of health insurance claims and specific health checkups of Japan (NDB): outline and patient-matching technique. bioRxiv 280008. doi:10.1101/280008
- Quality indicators for acute cardiovascular diseases: a scoping review.BMC Health Serv Res. 2022; 22: 862
- Evaluating the quality of medical care.Milbank Q. 2005; 83: 691-729
- Performance of hospitals according to the ESC ACCA quality indicators and 30-day mortality for acute myocardial infarction: national cohort study using the United Kingdom Myocardial Ischemia National Audit Project (MINAP) register.Eur Heart J. 2017; 38: 974-982
- A validated prediction model for all forms of acute coronary syndrome: estimating the risk of 6-month postdischarge death in an international registry.JAMA. 2004; 29: 2727-2733
- 2020 ESC guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation.Eur Heart J. 2021; 42: 1289-1367
- Association between hospital process performance and outcomes among patients with acute coronary syndromes.JAMA. 2006; 295: 1912-1920
- Prescription rates of guideline-directed medications are associated with in-hospital mortality among Japanese patients with acute myocardial infarction: a report from JROAD-DPC study.J Am Heart Assoc. 2019; 8e009692
- Cluster-randomised trial to evaluate the effects of a quality improvement program on management of non-ST-elevation acute coronary syndromes: the European Quality Improvement Programme for Acute Coronary Syndromes (EQUIP-ACS).Am Heart J. 2011; 162: 700-707.e1
- Acute myocardial infarction: a comparison of short-term survival in national outcome registries in Sweden and the UK.Lancet. 2014; 383: 1305-1312
- Survey on medical cardiovascular disease 2018.(Available at)http://www.j-circ.or.jp/jittai_chosa/jittai_chosa2018web.pdfDate accessed: October 6, 2021
- Increasing cardiac rehabilitation participation from 20% to 70%: a road map from the Million Hearts Cardiac Rehabilitation Collabourative.Mayo Clin Proc. 2017; 92: 234-242
- Cardiac rehabilitation after myocardial infarction in the community.J Am Coll Cardiol. 2004; 44: 988-996
Article info
Publication history
Published online: December 07, 2022
Accepted:
December 1,
2022
Received:
August 2,
2022
Publication stage
In Press Journal Pre-ProofFootnotes
See editorial by Vervoort et al., pages xxx-xxx of this issue.
See page 8 for disclosure information.
Identification
Copyright
© 2023 Published by Elsevier Inc. on behalf of the Canadian Cardiovascular Society.
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- Quality of Coronary Care: Reducing Practice VariabilityCanadian Journal of Cardiology