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Canadian Journal of Cardiology

Detection of Myocardial Injury After Noncardiac Surgery: Levelling the Troponin Playing Field

Published:January 11, 2023DOI:https://doi.org/10.1016/j.cjca.2023.01.007
      The troponin complex is made up of regulatory proteins found in cardiac myocytes that are integral to efficient cardiac muscle contraction. The complex is made up of 3 subunits: troponin C (TnC), troponin I (TnI), and troponin T (TnT). During myocardial ischemia, downstream hypoxic effects lead to myocyte cell death and rupture of the cell membrane.
      • Park K.C.
      • Gaze D.C.
      • Collinson P.O.
      • Marber M.S.
      Cardiac troponins: from myocardial infarction to chronic disease.
      This leads to measurable troponin levels in the circulation.
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