Canadian Journal of Cardiology
Case Report|Articles in Press

Combined use of NoblestitchTM EL system and Amplatzer device to close a patent foramen ovale with complex anatomy

Published:February 14, 2023DOI:
      Patent foramen ovale (PFO) is associated with cryptogenic stroke in young patients. In these cases, trans-catheter PFO closure is indicated either with a device implantation or with a suture-mediated PFO closure system (NobleStitchTM EL, Kardia, Milan, Italy) to prevent further cerebral ischemic events. However, the presence of a complex anatomy might require advanced technical skills. We herewith describe the first case of combined use of the NobleStitchTM EL system with an Amplatzer PFO Occluder (Abbott, Plymouth, USA) device to close a complex PFO characterized by a wide inter-atrial aneurysm, a long stiff tunnel and a thickened septum secundum.
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