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Canadian Journal of Cardiology
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    • Cover Image - Canadian Journal of Cardiology, Volume 39, Issue 5
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  • Journal News and Commentary

    Use of Renin-Angiotensin System Blockers During the COVID-19 Pandemic: Early Guidance and Evolving Evidence

    Canadian Journal of Cardiology
    Vol. 36Issue 8p1180–1182Published online: June 2, 2020
    • Ricky D. Turgeon
    • Shelley Zieroth
    • David Bewick
    • Chi-Ming Chow
    • Brian Clarke
    • Simone Cowan
    • and others
    Cited in Scopus: 3
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      The COVID-19 pandemic invoked the need for prompt guidance and rapid research to address emerging clinical questions. In response to early theoretical concerns regarding the use of renin-angiotensin system (RAS) blockers, including angiotensin-converting enzyme inhibitors (ACEIs), angiotensin II receptor blockers (ARBs), and angiotensin receptor–neprilysin inhibitors (ARNIs) during the COVID-19 pandemic, the Canadian Cardiovascular Society (CCS) and Canadian Heart Failure Society (CHFS) issued guidance to continue these therapies among patients with heart failure and hypertension.
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